Philippines Health News API

{
    "totalArticles": 88484,
    "articles": [
        {
            "id": "5c492db09ef7fc638592eee9bc511c93",
            "title": "Inspiratory muscle training and trunk control exercises on respiratory strength and motor function in spinal muscular atrophy: randomized controlled trial",
            "description": "Spinal muscular atrophy (SMA) is a progressive neuromuscular disorder characterized by respiratory muscle weakness and impaired functional capacity. This study aimed to evaluate the effects of respiratory exercises, inspiratory muscle training (IMT), and trunk control training in children with SMA. Thirty-eight children (10.21 ± 4.56 years) with SMA were randomly assigned to two groups. Pulmonary rehabilitation group (PRG, n = 19), performed diaphragmatic, pursed-lip, and segmental breathing exercises plus IMT at 30% maximal inspiratory pressure, twice daily for 8 weeks. Trunk control group (TCG, n = 19) received the same respiratory program with additional trunk exercises, three times a week. Primary outcomes were respiratory muscle strength (MIP, MEP), pulmonary function (FVC, FEV1, PEF), and peak cough flow (PCF). Secondary outcomes were trunk control (TCMS), upper limb function (RULM), and motor performance (HFMSE). Both groups demonstrated significant within-group improvements in respiratory strength and motor outcomes (p < 0.05). MIP increased with large effect sizes (PRG: d = 1.039; TCG: d = 1.556). Notably, TCG showed additional significant gains in static sitting balance (p < 0.05), selective movement control (p < 0.001), and RULM (p < 0.05). Although between-group differences were not statistically significant, effect sizes indicated clinically relevant advantages favoring the combined intervention. Combining IMT with trunk control training appears safe, feasible, and clinically beneficial in children with SMA.",
            "content": "Lefebvre, S. et al. Identification and characterization of a spinal muscular atrophy-determining gene. Cell 80, 155–165 (1995).\nVerhaart, I. E. C. et al. Prevalence, incidence and carrier frequency of 5q-linked spinal muscular atrophy - A literature ... [9367 chars]",
            "url": "https://www.nature.com/articles/s41598-025-32566-x?error=cookies_not_supported&code=f65d6728-66f0-4f5d-8b6a-ecaa1878ecf6",
            "image": "https://www.nature.com/static/images/favicons/nature/favicon-48x48-b52890008c.png",
            "publishedAt": "2025-12-20T03:53:17Z",
            "lang": "en",
            "source": {
                "id": "7abf0df285fbe93cdccffcc7c4088737",
                "name": "Nature",
                "url": "https://www.nature.com"
            }
        },
        {
            "id": "696a820e8e5aaa694017e4c9890ce9e2",
            "title": "Gene Solutions Concludes Successful ESMO Asia Congress 2025 with AI-Powered Multi-Omics Liquid Biopsy Symposium and Two Best Poster Awards",
            "description": "SINGAPORE, Dec. 20, 2025 /PRNewswire/ -- Gene Solutions, a pioneering genetic testing company, announced key achievements at the European Society for Medical Oncology (ESMO) Asia Congress 2025-held in Singapore on December 5-7. Highlights included a full-house symposium, seven scientific abstracts with two earning Best Poster designations, and meaningful engagement with thousands of oncologists from across the Asia-Pacific region at the company's exhibition booth.",
            "content": "SINGAPORE, Dec. 20, 2025 /PRNewswire/ -- Gene Solutions, a pioneering genetic testing company, announced key achievements at the European Society for Medical Oncology (ESMO) Asia Congress 2025-held in Singapore on December 5-7. Highlights included a ... [7914 chars]",
            "url": "https://www.manilatimes.net/2025/12/20/tmt-newswire/pr-newswire/gene-solutions-concludes-successful-esmo-asia-congress-2025-with-ai-powered-multi-omics-liquid-biopsy-symposium-and-two-best-poster-awards/2247367",
            "image": "https://www.manilatimes.net/manilatimes/uploads/images/2025/12/20/875157.jpg",
            "publishedAt": "2025-12-20T03:29:45Z",
            "lang": "en",
            "source": {
                "id": "e3ad8bbf7dbe3c3defc56a8393455066",
                "name": "The Manila Times",
                "url": "https://www.manilatimes.net"
            }
        },
        {
            "id": "5bbaeef69642a578cc107610fe8a8c98",
            "title": "Genetic, Inflammatory Predictors of Nondilated Left Ventricular Cardiomyopathy Progression",
            "description": "Genetics played a major role in predicting worsening LVEF, progressing to a dilated cardiomyopathy phenotype, and a combined end point of both.",
            "content": "Nearly 4 in 10 patients with nondilated left ventricular cardiomyopathy (NDLVC) experienced clinically meaningful disease progression over long-term follow-up, according to a large multicenter analysis published in the Canadian Journal of Cardiology.... [3668 chars]",
            "url": "https://www.ajmc.com/view/genetic-inflammatory-predictors-of-nondilated-left-ventricular-cardiomyopathy-progression",
            "image": "https://cdn.sanity.io/images/0vv8moc6/ajmc/fc627aa694d96b0a733f3e350cf1f132ab89bf3b-6720x4480.jpg",
            "publishedAt": "2025-12-19T22:50:51Z",
            "lang": "en",
            "source": {
                "id": "44c3dc8c76228ef5cb2e596d2bd52f75",
                "name": "The American Journal of Managed Care® (AJMC®)",
                "url": "https://www.ajmc.com"
            }
        }
    ]
}