Philippines Health News API

{
    "totalArticles": 100476,
    "articles": [
        {
            "id": "918daeca891cb789e0f9368d741ddd8d",
            "title": "A Case Report and Literature Review",
            "description": "Introduction: The term “carcinoma ex pleomorphic adenoma” (CXPA) is used to denote the malignant transformation of a preexisting pleomorphic adenoma. This condition is uncommon, with an incidence ranging from 2% to 15% of malignant salivary gland tumors. The transformation of the lesion into squamous cell carcinoma is an exceptional histological variant. We present a rare case with a particularly prolonged course and complex multidisciplinary management in a setting with limited resources. Observation: A 74-year-old patient with no significant past medical history was admitted for a large, ulcerated, and nodular mass in the right parotid gland that had been present for more than 40 years. Imaging studies revealed a locally advanced tumor associated with cervical lymphadenopathy. The initial biopsy revealed a diagnosis of squamous cell carcinoma. Subsequent to the administration of neoadjuvant chemotherapy, a parotidectomy was performed in conjunction with a neck dissection and reconstruction utilizing a pectoralis major flap. A final histological examination confirmed the presence of squamous cell carcinoma arising from a pleomorphic adenoma. The patient underwent adjuvant treatment, which included radiation therapy and chemotherapy. The subsequent one-year follow-up revealed no evidence of recurrence. Conclusion: This case exemplifies the potential progression of overlooked pleomorphic adenomas and underscores the significance of a comprehensive histological diagnosis and early multidisciplinary management.",
            "content": "1. Introduction\nSalivary gland tumors account for about 5% of head and neck neoplasia and are characterized by great histological diversity [1]. Pleomorphic adenoma is the most common benign parotid tumor, with an estimated risk of malignant transfor... [6330 chars]",
            "url": "https://www.scirp.org/journal/paperinformation?paperid=151822",
            "image": "https://file.scirp.org/image/ojst2024061816383964.jpg",
            "publishedAt": "2026-06-11T07:17:50Z",
            "lang": "en",
            "source": {
                "id": "48f641eab3fd1aa330e8db4cb1cfe74e",
                "name": "SCIRP Open Access",
                "url": "https://www.scirp.org"
            }
        },
        {
            "id": "c25852024bca228461edc0779e8800bd",
            "title": "New low-cost artificial mitral valve mimics human tissue to study disease",
            "description": "Researchers at RCSI University of Medicine and Health Sciences have developed an artificial model of the mitral heart valve that faithfully mimics the valve's complex mechanical behavior in the human heart.",
            "content": "Researchers at RCSI University of Medicine and Health Sciences have developed an artificial model of the mitral heart valve that faithfully mimics the valve's complex mechanical behavior in the human heart. The study could help researchers better und... [2253 chars]",
            "url": "https://www.news-medical.net/news/20260611/New-low-cost-artificial-mitral-valve-mimics-human-tissue-to-study-disease.aspx",
            "image": "https://www.news-medical.net/image-handler/picture/2017/1/Anatomy_of_Human_Heart.-Liya_Graphics_5ac9d64765b747899bc4a9ef77468432-620x480.jpg",
            "publishedAt": "2026-06-11T07:17:00Z",
            "lang": "en",
            "source": {
                "id": "f2ca7a45d20357cb42858868cb4a4946",
                "name": "News-Medical",
                "url": "https://www.news-medical.net"
            }
        },
        {
            "id": "75305d3d152dc631f6bc3b779b5b4c69",
            "title": "Ischemic Bowel as a Thrombotic Complication of COVID",
            "description": "Background: Coronavirus disease 2019 (COVID-19) is now recognized as a multisystem illness associated with a significant risk of thrombotic complications due to a hypercoagulable state. While venous thromboembolism is well documented, gastrointestinal ischemia remains a rare but severe manifestation. The incidence, clinical course, and outcomes of COVID-19-associated ischemic bowel are not well characterized, though available reports suggest high mortality. Proposed mechanisms include endothelial injury, inflammatory-mediated coagulation activation, and elevated prothrombotic factors. Case: A 67-year-old male presented to the emergency department with several days of generalized weakness and exertional dyspnea. Initial diagnostic considerations included anemia, dehydration, electrolyte abnormalities, and infection. Further evaluation revealed acute COVID-19 infection complicated by thrombotic disease resulting in ischemic bowel. His hospital course was prolonged and complex, marked by multiple complications and progressive functional decline. Despite aggressive medical management and supportive care, his prognosis remained poor. He was ultimately discharged to a long-term acute care facility with a tracheostomy tube, enteral feeding dependence, and continued mechanical ventilation. Conclusion: This case underscores the prothrombotic potential of COVID-19-associated hypercoagulability and highlights ischemic bowel as a rare yet devastating complication. Clinicians should maintain a high index of suspicion for thrombotic events in patients with COVID-19, even when initial symptoms are nonspecific, as delayed recognition may result in significant morbidity and mortality.",
            "content": "1. Introduction\nCoronavirus disease 2019 (COVID-19), first reported in December 2019, was initially described as primarily respiratory illness but is now widely recognized as a multisystem disease. Emerging evidence suggests that infection with sever... [13183 chars]",
            "url": "https://www.scirp.org/journal/paperinformation?paperid=151817",
            "image": "https://file.scirp.org/image/crcm2025082817051374.png",
            "publishedAt": "2026-06-11T06:27:38Z",
            "lang": "en",
            "source": {
                "id": "48f641eab3fd1aa330e8db4cb1cfe74e",
                "name": "SCIRP Open Access",
                "url": "https://www.scirp.org"
            }
        }
    ]
}