Philippines Health News API

{
    "totalArticles": 106974,
    "articles": [
        {
            "id": "9e79f3e2743c8d26ad1c6320330f114a",
            "title": "Novo Nordisk to present new data on Wegovy®, women with obesity and next-generation weight loss treatments at European Congress on Obesity",
            "description": "Analyses of the higher dose of Wegovy® (semaglutide 7.2 mg) and Wegovy® pill (oral semaglutide 25 mg) show how fast and how much sustained weight loss people who responded early to treatment achievedWegovy® (semaglutide 2.4 mg and 7.2 mg) clinical and real-world data exploring its role in managing menopausal symptoms, including weight gain and migraine, and lowering cardiovascular riskData on next-generation obesity pipeline, including the advanced combined amylin and GLP-1 receptor analoguesBagsværd, Denmark, 28 April 2026 - Novo Nordisk will present new clinical data and real-world evidence at the European Congress on Obesity, 12-15 May in Istanbul, Turkey. The full data, 52 abstracts, span Wegovy® (semaglutide 2.4 mg), higher-dose Wegovy® (semaglutide 7.2 mg), Wegovy® pill (oral semaglutide 25 mg), and CagriSema (cagrilintide 2.4 mg/semaglutide 2.4 mg), an investigational first-in-class combination of a GLP-1 receptor agonist and a long-acting amylin analogue.",
            "content": "Analyses of the higher dose of Wegovy® (semaglutide 7.2 mg) and Wegovy® pill (oral semaglutide 25 mg) show how fast and how much sustained weight loss people who responded early to treatment achieved\nWegovy® (semaglutide 2.4 mg and 7.2 mg) clinical a... [8024 chars]",
            "url": "https://www.manilatimes.net/2026/04/28/tmt-newswire/globenewswire/novo-nordisk-to-present-new-data-on-wegovy-women-with-obesity-and-next-generation-weight-loss-treatments-at-european-congress-on-obesity/2330303",
            "image": "https://www.manilatimes.net/manilatimes/uploads/images/2026/04/28/1032799.jpg",
            "publishedAt": "2026-04-28T12:02:14Z",
            "lang": "en",
            "source": {
                "id": "e3ad8bbf7dbe3c3defc56a8393455066",
                "name": "The Manila Times",
                "url": "https://www.manilatimes.net"
            }
        },
        {
            "id": "712f55eeae2b089c8ae3c0191349aea8",
            "title": "Pomegranate Compound May Help Protect Against Heart Disease, Reveals Study",
            "description": "When you eat pomegranate, your body breaks down a major healthy nutrient called punicalagin (PC) into smaller pieces called urolithins that showed the strongest protective effects.",
            "content": "Pomegranate is a nutrient-rich fruit known for its numerous health benefits. It is packed with antioxidants, particularly punicalagins and anthocyanins, which help protect your cells from damage caused by free radicals. It is rich in vitamin C and K,... [2979 chars]",
            "url": "https://www.ndtv.com/health/pomegranate-compound-may-help-protect-against-heart-disease-reveals-study-11420347",
            "image": "https://c.ndtvimg.com/2025-07/o0bbs7pk_pomegranate_625x300_02_July_25.jpg?im=FeatureCrop,algorithm=dnn,width=1200,height=738",
            "publishedAt": "2026-04-28T11:00:34Z",
            "lang": "en",
            "source": {
                "id": "5775709b019bb5c3dae707e7b660f89e",
                "name": "NDTV",
                "url": "https://www.ndtv.com"
            }
        },
        {
            "id": "ce4462d57776577f0ef03fed7a3be615",
            "title": "Role of hypertrophic adipocytes, collagen VI, and CD38 in adipose tissue fibrosis in obesity",
            "description": "Adipose tissue fibrosis is associated with metabolic alterations in patients with obesity and involves three major collagen types: fibrillar collagens I and III and non-fibrillar collagen VI. In this study, fibrosis was found to be significantly increased only in visceral adipose tissue in patients with obesity (4.7% vs. 2.5% in controls, p < 0.001), whereas no significant difference was observed in subcutaneous adipose tissue. Transmission electron microscopy and high-resolution scanning electron microscopy suggested that hypertrophic adipocytes may contribute to the production of fibrillar collagens I and III. In vitro data were consistent with this interpretation. Expression of the COL6 gene, which encodes the non-fibrillar collagen VI, was reduced in adipose tissue from obese patients. Notably, patients carrying mutations in COL6 genes displayed increased fibrosis even in subcutaneous fat, approximately 6.5-fold higher than controls in the patient with the severe form (Ullrich) and 2.8-fold higher in two patients with the milder form (Bethlem). Approximately 15% of adipocytes in obese tissue appeared stressed or dead (perilipin-1 negative), and the associated infiltrating macrophages exhibited increased expression of CD38, an ectoenzyme implicated in systemic fibrosis. Correlations with gene expression also indicated the importance of myofibroblasts and the extracellular-matrix peptidase D. Taken together, our data suggest that obese adipocytes may contribute to fibrillar collagen production and identify collagen VI and CD38 as potential molecular contributors, consistent with the concept that adipose tissue fibrosis in humans has a multifactorial origin.",
            "content": "Adipose tissue fibrosis is associated with metabolic alterations in patients with obesity and involves three major collagen types: fibrillar collagens I and III and non-fibrillar collagen VI. In this study, fibrosis was found to be significantly incr... [2508 chars]",
            "url": "https://www.nature.com/articles/s41598-026-49848-7?error=cookies_not_supported&code=7d419bd1-21c0-4006-808c-9c796ce17664",
            "image": "https://www.nature.com/static/images/favicons/nature/favicon-48x48-b52890008c.png",
            "publishedAt": "2026-04-28T08:58:31Z",
            "lang": "en",
            "source": {
                "id": "7abf0df285fbe93cdccffcc7c4088737",
                "name": "Nature",
                "url": "https://www.nature.com"
            }
        }
    ]
}