Philippines Business News API

{
    "totalArticles": 279038,
    "articles": [
        {
            "id": "916c3b7d09d9231f1c42024874415ce5",
            "title": "Crown Castle Announces First Quarter 2026 Earnings Conference Call Details",
            "description": "The Investor Relations website contains information about Crown Castle's business for stockholders, potential investors, and financial analysts.",
            "content": "HOUSTON, April 08, 2026 (GLOBE NEWSWIRE) -- Crown Castle Inc. (NYSE: CCI) (\"Crown Castle\") plans to release its first quarter 2026 results on Wednesday, April 22, 2026, after the market closes. In conjunction with the release, Crown Castle has schedu... [1239 chars]",
            "url": "https://investor.crowncastle.com/news-releases/news-release-details/crown-castle-announces-first-quarter-2026-earnings-conference",
            "image": "https://investor.crowncastle.com/sites/g/files/knoqqb36226/files/favicon_0.ico",
            "publishedAt": "2026-04-08T21:59:00Z",
            "lang": "en",
            "source": {
                "id": "39ead17ec7cb7d7303c6548c692704ba",
                "name": "Crown Castle",
                "url": "https://investor.crowncastle.com"
            }
        },
        {
            "id": "103f0041ccb39466483a1afc255fdcdc",
            "title": "Multiomics and deep learning dissect regulatory syntax in human development",
            "description": "Transcription factors establish cell identity during development by binding regulatory DNA in a sequence-specific manner, often promoting local chromatin accessibility and regulating gene expression1. Mapping accessible chromatin offers critical insights into transcriptional control, but available datasets for human development are restricted to bulk tissue, single organs or single modalities2. Here we present the Human Development Multiomic Atlas, a single-cell atlas of chromatin accessibility and gene expression from 817,740 fetal cells across 12 organs, spanning 203 cell types and more than 1 million candidate cis-regulatory elements, many of which exhibit organ-specific in vivo enhancer activity. Deep learning models trained to predict accessibility from local DNA sequence unravel a comprehensive lexicon of motifs that influence accessibility, including composite motifs exhibiting distinct syntactic constraints that are predicted to mediate transcription factor cooperativity. We identify ‘hard’ syntactic rules requiring precise motif spacing and orientation, ‘soft’ rules allowing flexible motif arrangements, and ubiquitous motifs inhibiting accessibility. Model-based interpretation of genetic variants reveals that disruption of motifs with positive and negative effects is associated with concordant effects on gene expression. Our work delineates how motif syntax governs cell-type-specific chromatin accessibility and provides a foundational resource for decoding cis-regulatory logic and interpreting genetic variation during human development. The Human Development Multiomic Atlas catalogues single-cell accessibility and gene expression data from human fetal cells across 12 organs, enabling the inference of syntactic rules for motifs that govern cell-type-specific transcription factor binding and chromatin accessibility during human development.",
            "content": "Ethics statement\nDe-identified tissue samples were collected at Stanford University School of Medicine from elective termination of pregnancy procedures with informed consent for the research use of tissues in observance of relevant legal and institu... [46845 chars]",
            "url": "https://www.nature.com/articles/s41586-026-10326-9?error=cookies_not_supported&code=b65ed4d6-a9e3-4e17-b2c6-c28d747fefc5",
            "image": "https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs41586-026-10326-9/MediaObjects/41586_2026_10326_Fig1_HTML.png",
            "publishedAt": "2026-04-08T21:57:35Z",
            "lang": "en",
            "source": {
                "id": "7abf0df285fbe93cdccffcc7c4088737",
                "name": "Nature",
                "url": "https://www.nature.com"
            }
        },
        {
            "id": "762dd43d78411162924248080f1b801f",
            "title": "Rates Spark: As the dust settles, there’s still a price to pay",
            "description": "The belly of the curve suggests the growth outlook might already have taken a hit despite less hawkish pricing",
            "content": "All eyes remain on the Middle East and whether the ceasefire can hold. Data is less relevant, especially when it pertains to the month of February, such as the US personal spending and income data and the PCE deflator, the latter usually the Fed’s pr... [1074 chars]",
            "url": "https://think.ing.com/articles/rates-spark-as-the-dust-settles-theres-still-a-price-to-pay/",
            "image": "https://think.ing.com/uploads/hero/_w800h450/Rates_US_Iran_ceasefire_080426.jpg",
            "publishedAt": "2026-04-08T21:21:59Z",
            "lang": "en",
            "source": {
                "id": "7c8344ad5f4d66aa4a1689896e0c369d",
                "name": "ING THINK economic and financial analysis | ING THINK",
                "url": "https://think.ing.com"
            }
        }
    ]
}