Pakistan Science News API

{
    "totalArticles": 24820,
    "articles": [
        {
            "id": "ee72b71fa0c2f5ade153e8eda6404d02",
            "title": "NASA head defends Artemis 3 crew of all men",
            "description": "NASA's administrator Jared Isaacman on Wednesday defended the makeup of the space agency's latest Artemis crew, an all-male group.Isaacman insisted in a lengthy social media post that the \"crew select...",
            "content": "NASA's administrator Jared Isaacman on Wednesday defended the makeup of the space agency's latest Artemis crew, an all-male group.\nThe nominations have earned criticism that NASA may have acted in accordance with President Donald Trump's direction to... [2076 chars]",
            "url": "https://sg.news.yahoo.com/nasa-head-defends-artemis-3-164403902.html",
            "image": "https://s.yimg.com/os/en/afp.com.sg/fb33ec3efcac30e56175cd174b62789b",
            "publishedAt": "2026-06-10T16:44:03Z",
            "lang": "en",
            "source": {
                "id": "d0f7288d14ec8c674636416b7d8b268b",
                "name": "Yahoo News Singapore",
                "url": "https://sg.news.yahoo.com"
            }
        },
        {
            "id": "a8c55786bc056a473a005ae2910f5267",
            "title": "Nature Study: Arctic Icebergs Increasing",
            "description": "The number of icebergs in the Arctic has increased sharply since the 2000s. This is due to the destabilisation of large glaciers in north-east",
            "content": "The number of icebergs in the Arctic has increased sharply since the 2000s. This is due to the destabilisation of large glaciers in north-east Greenland and parts of the Russian Arctic as well as the increasing mobility of sea ice. The result: Stones... [6461 chars]",
            "url": "https://www.miragenews.com/nature-study-arctic-icebergs-increasing-1689950/",
            "image": "https://cdn1.miragenews.com/tmp_cache?cdn=images.unsplash.com%2Fphoto-1532619675605-1ede6c2ed2b0%3Fixlib%3Drb-4.0.3%26amp%3Bixid%3DMnwxMjA3fDB8MHxwaG90by1wYWdlfHx8fGVufDB8fHx8%26amp%3Bauto%3Dformat%26amp%3Bfit%3Dcrop%26amp%3Bw%3D1170%26amp%3Bq%3D80",
            "publishedAt": "2026-06-10T15:14:00Z",
            "lang": "en",
            "source": {
                "id": "0368281c39ba31f7435685e8b620f675",
                "name": "Mirage News",
                "url": "https://www.miragenews.com"
            }
        },
        {
            "id": "049a53c150050f971b31bcda9c138c5d",
            "title": "Mutation-biased adaptation is consequential even in large bacterial populations",
            "description": "Because mutation rates vary widely across genomes and environments, natural selection is typically presented with highly biased variation. Yet, the idea that mutational tendencies can influence adaptation is still controversial. While mutation-driven adaptation has been observed in diverse taxa, critics contend it reflects small populations or weak-effect mutations. Therefore, the importance and generality of this phenomenon remain unclear, largely due to a lack of empirical tests across broad population-size gradients and multiple fitness-relevant traits. Here, we address this gap using a system in which two Escherichia coli mutator lineages evolve antibiotic resistance via two mutationally favoured, yet genetically distinct, routes. Simulations and experiments show that the scaling of mutation-biased adaptation with population size is complex, highly dependent on biological details, and – most critically – on how closely mutation bias aligns with selection. Contrary to the common view, we find that mutation-biased adaptation may not wane in large populations, but instead intensify depending on the bias. Crucially, we demonstrate that distinct mutation biases produce markedly different collateral sensitivity profiles to multiple antibiotics, even at large population sizes. Our findings suggest that mutation-biased adaptation may be widespread, with far-reaching and unpredictable consequences both within and beyond the original selective context. Adaptation is assumed to proceed by survival of the fittest. The study shows that mutation bias can drive adaptation via survival of the likeliest, steering bacteria along divergent paths to resistance with major consequences for control strategies.",
            "content": "This work was supported by the European Commission under the Horizon Europe framework (Marie Skłodowska-Curie Individual Fellowship, MSCA-IF 101109457, to J.B.), the Agencia Estatal de Investigación (Proyectos de I + D + i, PID2022-142857NB-I00, to A... [1322 chars]",
            "url": "https://www.nature.com/articles/s41467-026-74044-6?error=cookies_not_supported&code=b640fff6-7afb-47d6-94cc-276df85db3ca",
            "image": "https://www.nature.com/static/images/favicons/nature/favicon-48x48-b52890008c.png",
            "publishedAt": "2026-06-10T08:55:09Z",
            "lang": "en",
            "source": {
                "id": "7abf0df285fbe93cdccffcc7c4088737",
                "name": "Nature",
                "url": "https://www.nature.com"
            }
        }
    ]
}