Pakistan Science News API

{
    "totalArticles": 20084,
    "articles": [
        {
            "id": "fd68e83096afb73507df0546d426b75e",
            "title": "Galactic Monsters Grew in Cocoons Like Giant Bugs, Scientists Say",
            "description": "Astronomers say that ancient almost impossibly massive \"Little Red Dots\" may be black holes trapped in \"cocoons.\"",
            "content": "How the most massive objects in the universe first formed is one of the biggest headscratchers in astrophysics. With more advanced telescopes, astronomers have found fully formed galaxies and colossal black holes earlier and earlier in the cosmos, ju... [3706 chars]",
            "url": "https://futurism.com/space/james-webb-red-dots",
            "image": "https://futurism.com/wp-content/uploads/2026/01/james-webb-red-dots_e58e15.jpg?quality=85&w=1200",
            "publishedAt": "2026-02-01T15:30:00Z",
            "lang": "en",
            "source": {
                "id": "bfcf3640a8a972f0d68e8dd134988385",
                "name": "Futurism",
                "url": "https://futurism.com"
            }
        },
        {
            "id": "e4061ac8346c8779607cd32da24dc98a",
            "title": "Ultrasound helmet reaches deep into the brain without surgery",
            "description": "New ultrasound helmet precisely targets deep brain regions without surgery, opening doors for research and treatment of brain disorders.",
            "content": "For decades, scientists have searched for a safe way to reach deep parts of the human brain without cutting into the skull. That goal now feels closer. Researchers from University College London and the University of Oxford have developed an ultrasou... [7183 chars]",
            "url": "https://www.thebrighterside.news/post/ultrasound-helmet-reaches-deep-into-the-brain-without-surgery/",
            "image": "https://www.thebrighterside.news/uploads/2026/01/ultrasound-helmet.png?auto=webp",
            "publishedAt": "2026-02-01T12:51:00Z",
            "lang": "en",
            "source": {
                "id": "112bf679e5854b6527eea31fa42dbada",
                "name": "The Brighter Side of News",
                "url": "https://www.thebrighterside.news"
            }
        },
        {
            "id": "a63df8f1f2c926493e50bd0ecb714feb",
            "title": "A Citrus medica stem cutting-based platform for rapid screening of therapeutic compounds against Candidatus Liberibacter asiaticus",
            "description": "Huanglongbing (HLB), caused by Candidatus Liberibacter asiaticus (CLas), is the most devastating citrus disease worldwide. Developing effective therapies remains a major challenge, as CLas colonizes the host phloem systemically and cannot be cultured in vitro. This study presents a rapid, reproducible, and cost-effective in vivo platform for screening bacteriostatic and bactericidal compounds using CLas-infected citron (Citrus medica (L.) Osbeck) stem cuttings. Among seven citrus genotypes tested, citron stem cuttings exhibited superior rooting performance and uniform vegetative growth. Four propagation protocols were developed and assessed based on the dynamics of rooting and shoot growth, CLas colonization, and the response to oxytetracycline (OTC) treatment. CLas + stem cuttings were treated with OTC via drenching at different developmental root stages. The roots or new vegetative flushes were sampled for bacterial quantification by qPCR. In Protocol 2, in which treatments were applied and sampled 14 and 35 days after planting (DAP) respectively, OTC-treated roots achieved the highest suppression of CLas and a lower incidence of CLas + rooted cuttings compared to non-treated roots. Time-course analysis showed that OTC delayed bacterial establishment in root tissues, with maximal suppression observed at 35 DAP. The proposed protocols simulate the natural progression of systemic infection in citrus plants, allow the assessment of phytotoxicity, and offer a scalable technology that does not underestimate the efficacy of future bactericidal candidates. This platform significantly reduces time and cost compared to traditional seedling or nursery tree experiments and enhances the early-phase screening of antimicrobial compounds. Altogether, this stem cutting-based approach represents a biologically relevant, scalable tool to accelerate therapeutic discovery and strengthen integrated HLB management strategies.",
            "content": "Bové, J. M. Huanglongbing or yellow shoot, a disease of Gondwanan origin: will it destroy citrus worldwide? Phytoparasitica 42, 579–583 (2014).\nBové, J. M. Huanglongbing: A Destructive, Newly-Emerging, Century-Old disease of citrus. Journal Plant. Pa... [11311 chars]",
            "url": "https://www.nature.com/articles/s41598-026-37186-7?error=cookies_not_supported&code=73739ef0-908a-4019-b13f-245ed482b3ab",
            "image": "https://www.nature.com/static/images/favicons/nature/favicon-48x48-b52890008c.png",
            "publishedAt": "2026-02-01T11:44:01Z",
            "lang": "en",
            "source": {
                "id": "7abf0df285fbe93cdccffcc7c4088737",
                "name": "Nature",
                "url": "https://www.nature.com"
            }
        }
    ]
}