Pakistan Health News API

{
    "totalArticles": 64852,
    "articles": [
        {
            "id": "eef7825edae3d54f200e1d3a0205deb8",
            "title": "Brain health shaped by lifetime mental, physical, environmental and lifestyle factors",
            "description": "More research is needed to assess how everyday factors from early life through adulthood influence brain health and affect the risk of developing cognitive decline, dementia or stroke, according to a new American Heart Association scientific statement.",
            "content": "Statement Highlights:\nAn individual’s brain health is influenced by their psychological health, environment, sleep quality, social conditions and chronic health conditions over a lifetime. Life events and experiences even in early life also affect lo... [15041 chars]",
            "url": "https://newsroom.heart.org/news/brain-health-shaped-by-lifetime-mental-physical-environmental-and-lifestyle-factors",
            "image": "https://iprsoftwaremedia.com/67/files/20179/59f343112cfac22ba70b5c24_Head%20and%20brain%20illustration/Head%20and%20brain%20illustration_hero.jpg",
            "publishedAt": "2026-04-28T09:06:52Z",
            "lang": "en",
            "source": {
                "id": "6cacf118472bb930a32eb54ae379a24b",
                "name": "www.heart.org",
                "url": "https://newsroom.heart.org"
            }
        },
        {
            "id": "12db58a2323e437eedd885afb0754611",
            "title": "A neurological prognostic nomogram integrating biomarkers and clinical indicators for surgically treated patients with osteoporotic spinal fracture and spinal cord injury",
            "description": "To construct and validate a prediction model of neurological rehabilitation for patients with osteoporotic spinal fracture combined with spinal cord injury based on the expression of serum neurotrophic factor (Neuritin) and transforming growth factor β1 (TGF-β1 ), so as to provide basis for accurate clinical rehabilitation. A total of 189 patients with osteoporotic spinal fracture combined with spinal cord injury who were admitted to our hospital from January 2022 to September 2024 were included in the study. A random 7:3 score was used as the training set (n = 132) and validation set (n = 57). In the training set, independent influencing factors were screened by univariate and multivariate Logistic regression analysis, and a Nomogram model was constructed. The model performance was evaluated by using the consistency index (C-index), calibration curve, and receiver operating characteristic curve (ROC), and was verified in the validation set. There was no significant difference in baseline data between the training set and the validation set (P > 0.05). Multivariate logistic analysis showed that serum Neuritin (ng/mL, OR = 1.285), TGF-β1 (ng/mL, OR = 0.979), vertebral compression degree (%) (OR = 0.960), spinal canal space-occupying rate (%) (OR = 0.879), 25-hydroxyvitamin D (ng/mL, OR = 1.103), and alkaline phosphatase (U/L, OR = 0.973) were the independent factors for poor neurological rehabilitation (all P < 0.05). The C-index for the nomogram model was 0.842 and 0.821 in the training and validation sets, respectively, the calibration curve fitted well, and the area under the ROC curve (AUC) was 0.850 (95% CI: 0.75–0.95) and 0.826 (95% CI: 0.65-1.00), respectively. The Nomogram model constructed based on serum levels of Neuritin and TGF-β1 can effectively predict the neurological rehabilitation effects of patients with osteoporotic spinal fracture combined with spinal cord injury, and has potential clinical application value.",
            "content": "To construct and validate a prediction model of neurological rehabilitation for patients with osteoporotic spinal fracture combined with spinal cord injury based on the expression of serum neurotrophic factor (Neuritin) and transforming growth factor... [1711 chars]",
            "url": "https://www.nature.com/articles/s41598-026-50468-4?error=cookies_not_supported&code=ae54226b-eeb9-4f9e-9902-b3f88817a57e",
            "image": "https://www.nature.com/static/images/favicons/nature/favicon-48x48-b52890008c.png",
            "publishedAt": "2026-04-28T08:58:31Z",
            "lang": "en",
            "source": {
                "id": "7abf0df285fbe93cdccffcc7c4088737",
                "name": "Nature",
                "url": "https://www.nature.com"
            }
        },
        {
            "id": "0408ac5c63ed8eecbc3db4a23c5fce3f",
            "title": "Evolution of ancient humans may have been influenced by malaria",
            "description": "Humans have been living alongside malaria for tens of thousands of years.",
            "content": "Some of the smallest organisms might have influenced our own evolutionary path.\nA new study has found that the distribution of malaria in Africa in the last 70,000 years could have influenced where our ancient ancestors were living and as a result ho... [5240 chars]",
            "url": "https://www.nhm.ac.uk/discover/news/2026/april/evolution-of-ancient-humans-may-have-been-influenced-by-malaria.html",
            "image": "https://www.nhm.ac.uk/content/dam/nhm-www/discover/human-distribution-malaria/human-distribution-malaria-watering-hole-full-width.jpg",
            "publishedAt": "2026-04-28T08:45:11Z",
            "lang": "en",
            "source": {
                "id": "7d26ca1a1edd12ebd50ea87d4938d7ed",
                "name": "Natural History Museum",
                "url": "https://www.nhm.ac.uk"
            }
        }
    ]
}