Pakistan Health News API

{
    "totalArticles": 61512,
    "articles": [
        {
            "id": "0407e8cbc2badeb084a78b6775360ba3",
            "title": "Pakistani hospitals preparing for arrival of free childhood cancer medicines in 2026 under WHO-Pakistan agreement",
            "description": "News and Press Release in English on Pakistan about Health; published on 12 Feb 2026 by WHO",
            "content": "Four facilities are finalizing preparations to receive the supplies before the end of the year, while seven additional centres aim to be ready for 2027\n12 February 2026, Islamabad – Four Pakistani hospitals are completing preparations to start receiv... [4501 chars]",
            "url": "https://reliefweb.int/report/pakistan/pakistani-hospitals-preparing-arrival-free-childhood-cancer-medicines-2026-under-who-pakistan-agreement",
            "image": "https://reliefweb.int/modules/custom/reliefweb_meta/images/icons/Pakistan_PAK.png",
            "publishedAt": "2026-02-12T13:21:55Z",
            "lang": "en",
            "source": {
                "id": "9a34c7c24e864969b24702b4191d00ad",
                "name": "ReliefWeb",
                "url": "https://reliefweb.int"
            }
        },
        {
            "id": "e521d7b2244d09803de9c770f07749dd",
            "title": "Pakistani hospitals preparing for arrival of free childhood cancer medicines in 2026 under WHO-Pakistan agreement",
            "description": "Four facilities are finalizing preparations to receive the supplies before the end of the year, while seven additional centres aim to be ready for 2027WHO and St. Jude Children’s Research Hospital experts visited...",
            "content": "Four facilities are finalizing preparations to receive the supplies before the end of the year, while seven additional centres aim to be ready for 2027\n12 February 2026, Islamabad – Four Pakistani hospitals are completing preparations to start receiv... [4486 chars]",
            "url": "https://www.emro.who.int/pak/pakistan-news/pakistani-hospitals-preparing-for-arrival-of-free-childhood-cancer-medicines-in-2026-under-who-pakistan-agreement.html",
            "image": "https://www.emro.who.int/images/stories/pakistan/WHO-and-St-Jude-experts-visit-Noori-Hospital-to-prepare-for-cancer-supply-delivery.jpg",
            "publishedAt": "2026-02-12T12:31:22Z",
            "lang": "en",
            "source": {
                "id": "35d1caab3c605630805c3820e32e74a1",
                "name": "emro.who.int",
                "url": "https://www.emro.who.int"
            }
        },
        {
            "id": "25a8c4ab5eb93a08a9fbccda73cac199",
            "title": "Bacterial colonization of tumors drives immune activation and checkpoint blockade efficacy",
            "description": "The tumor microenvironment (TME), which heavily influences immune checkpoint blockade (ICB) efficacy, is shaped by host-microbe interactions. Endogenous intratumoral bacteria have been implicated in efficacy of ICB, such as anti-PD-1 (aPD-1), however, their role in modulating the TME, and whether these TME interactions are represented in murine tumor models, remains unknown. Using 16S rRNA qPCR, sequencing, and culture-based methods on multiple murine tumor models, we identified intratumoral microbiota in MCA-205 tumors but not in MOC1 tumors, underscoring the role of tumor-intrinsic factors in shaping microbial colonization. In MCA-205 tumors, intratumoral microbiota increased dendritic cell (DC) maturation and CD8+ T cell infiltration and activation, boosting ICB therapeutic efficacy. Specific depletion of only the intratumoral microbiota abrogated these effects. We found these bacteria-dependent effects were not due to canonical TLR signaling, as aPD-1 efficacy was not reduced by blocking TLR signaling through MyD88 depletion or enhanced by adding E. coli into the TME. This suggests that specific microbial species or communities, rather than bacterial colonization alone, are required to modulate antitumor immunity. These results reveal that intratumoral microbiota, when present, can dictate ICB efficacy, highlighting the importance of understanding this variable in murine experiments aiming to optimize cancer immunotherapy.",
            "content": "Emerson, D. A., Rolig, A. S. & Redmond, W. L. Enhancing the generation of Eomes(hi) CD8(+) T cells augments the efficacy of OX40- and CTLA-4-Targeted immunotherapy. Cancer Immunol. Res. 9, 430–440. https://doi.org/10.1158/2326-6066.CIR-20-0338 (2021)... [10877 chars]",
            "url": "https://www.nature.com/articles/s41598-026-39758-z?error=cookies_not_supported&code=bf6cfe1a-3dca-4e75-879e-66a50e53817b",
            "image": "https://www.nature.com/static/images/favicons/nature/favicon-48x48-b52890008c.png",
            "publishedAt": "2026-02-12T10:38:57Z",
            "lang": "en",
            "source": {
                "id": "7abf0df285fbe93cdccffcc7c4088737",
                "name": "Nature",
                "url": "https://www.nature.com"
            }
        }
    ]
}