Botswana Health News API

{
    "totalArticles": 2089,
    "articles": [
        {
            "id": "244eec9c43fb51544ea7353fcb594c9d",
            "title": "Association of periodontitis with reduced kidney function and albuminuria in early chronic kidney disease: a population-based study",
            "description": "Periodontitis has been linked to chronic kidney disease (CKD) through systemic inflammation. However, evidence in early CKD remains limited. We analyzed 6 179 participants from a population-based cohort (median age 62 years; 51% women). Periodontitis was classified according to the 2017 American Academy of Periodontology / European Federation of Periodontology criteria. Kidney function was assessed by the combined creatinine- and cystatin C–based estimated glomerular filtration rate (eGFR) and urinary albumin-to-creatinine ratio (uACR). Associations of periodontitis stages and mean clinical attachment loss (CAL) with eGFR and uACR were examined using multivariable linear regression adjusted for age, sex, diabetes, and smoking. Mediation analyses tested indirect effects of high-sensitivity C-reactive protein (hsCRP) and interleukin-6 (IL-6). Prevalence of severe periodontitis increased from 14% in individuals with normal kidney function (eGFR ≥60 mL/min per 1.73 m²) to 36% in those with moderately reduced eGFR (<60 mL/min per 1.73 m²) and from 21% in individuals without albuminuria (<10 mg/g) to 32% in those with moderately increased albuminuria (29–300 mg/g). After adjustment, Stage IV periodontitis was independently associated with lower eGFR (β−1.08 mL/min per 1.73 m²; 95% CI−2.04 to −0.12) and higher Blom-transformed uACR (β 0.09; 95% CI 0.01–0.16) compared with Stage I/II. hsCRP partially mediated these associations, accounting for 35% of the association with eGFR and 10% with uACR. These findings suggest that both inflammatory and non-inflammatory pathways may link periodontitis to early CKD. Periodontitis was associated with reduced eGFR and higher uACR in early CKD. While overlapping risk factors contribute, an independent association remained, only partly explained by systemic inflammation.",
            "content": "Periodontitis, a chronic inflammatory disease affecting the tooth-supporting structures, is one of the most prevalent inflammatory conditions worldwide, affecting up to 50% of the global population.1,2,3 Its association with cardiovascular diseases h... [34023 chars]",
            "url": "https://www.nature.com/articles/s41368-026-00435-6?error=cookies_not_supported&code=1930ea45-6f8a-4373-a39e-0a06681f8b9d",
            "image": "https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs41368-026-00435-6/MediaObjects/41368_2026_435_Fig1_HTML.png",
            "publishedAt": "2026-04-06T00:03:11Z",
            "lang": "en",
            "source": {
                "id": "7abf0df285fbe93cdccffcc7c4088737",
                "name": "Nature",
                "url": "https://www.nature.com"
            }
        },
        {
            "id": "bd6299c353d8d195f228b329334affd0",
            "title": "Ex-Carnivore Paul Saladino Says Fruit 'Makes Up The Majority' Of His Diet Now",
            "description": "Former carnivore influencer Paul Saladino has said that fruit now “makes up the majority” of his diet, but he experiments with vegetables",
            "content": "Influencer Paul Saladino, who previously followed a strict carnivore diet, has said that fruit now “makes up the majority” of his food.\nSaladino, a meat-focused content creator who previously created content under his Carnivore MD moniker, has begun ... [2255 chars]",
            "url": "https://plantbasednews.org/lifestyle/health/ex-carnivore-paul-saladino-fruit-diet/",
            "image": "https://plantbasednews.org/app/uploads/2026/04/carnivore-diet-paul-saladino-fruit-2.jpg",
            "publishedAt": "2026-04-05T14:00:00Z",
            "lang": "en",
            "source": {
                "id": "dc382ee24b50796aaa67ae1d819da621",
                "name": "Plant Based News",
                "url": "https://plantbasednews.org"
            }
        },
        {
            "id": "8d9778ff293d072971c0e4e5c2073a24",
            "title": "Viruses can 'eavesdrop' on each other - and sometimes get tricked",
            "description": "Rival viruses can eavesdrop on each other’s chemical signals, sometimes triggering the wrong response and changing how infections unfold.",
            "content": "Viruses that infect bacteria don’t just attack – they communicate. Using chemical signals, they “talk” to each other to decide whether to destroy a host cell or lie low and wait for better conditions.\nBut new research shows those messages aren’t alwa... [6168 chars]",
            "url": "https://www.earth.com/news/viruses-can-eavesdrop-on-each-other-and-sometimes-get-tricked/",
            "image": "https://cff2.earth.com/uploads/2026/04/05070042/viruses-eavesdrop2.jpg",
            "publishedAt": "2026-04-05T13:52:13Z",
            "lang": "en",
            "source": {
                "id": "fca72a05020e12df547eedb79c870663",
                "name": "Earth.com",
                "url": "https://www.earth.com"
            }
        }
    ]
}