United States Health News API

{
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        {
            "id": "4d331a26a365900efcadea08a7e978d2",
            "title": "30 facts you were taught at school that aren't actually true anymore",
            "description": "Stacker puts together a list of facts you learned in school that are no longer true.",
            "content": "Facts you learned in school that are no longer true\nSchool curriculums contain plenty of useful subjects: algebra, grammar, chemistry. Of course, there are plenty of other lessons that didn't prove quite so accurate. From history classes that glossed... [9896 chars]",
            "url": "https://www.aol.com/news/30-facts-were-taught-school-130113867.html",
            "image": "https://s.yimg.com/ny/api/res/1.2/gJ3TXgkPdmzdF7edZNL54w--/YXBwaWQ9aGlnaGxhbmRlcjt3PTEyMDA7aD02NzU-/https://media.zenfs.com/en/aol_stacker_articles_387/d80c407f7fb93ed773aa99822e70d57c",
            "publishedAt": "2026-04-15T01:22:58Z",
            "lang": "en",
            "source": {
                "id": "4ff2d0fa568705d6b87ce5c9e310a16d",
                "name": "AOL.com",
                "url": "https://www.aol.com"
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        {
            "id": "33fc8892a83c428c97f442094aa73f0f",
            "title": "Polyclonal selection of immune checkpoint mutations in thyroid autoimmunity",
            "description": "Our immune system contains multiple checkpoints to prevent the activation of self-reactive lymphocytes. How some lymphocytes escape these constraints to cause autoimmune disease remains poorly understood. A long-standing hypothesis posits that somatic mutations in immune-regulatory genes may enable self-reactive lymphocytes to bypass tolerance checkpoints1–3, but testing this has been challenging due to technical limitations. Here, we use whole-exome and targeted NanoSeq4,5, an accurate single-molecule DNA sequencing protocol, to comprehensively search for driver mutations in autoimmune thyroid disease. This revealed many B cell clones convergently acquiring loss-of-function mutations in the key immune checkpoint genes TNFRSF14 (HVEM) and CD274 (PD-L1), as well as less frequent mutations in other immune genes. In highly inflamed biopsies, we detected tens to hundreds of independent immune checkpoint mutant clones. Laser microdissection, methylation sequencing, spatial transcriptomics, immunostaining, single-nucleus DNA sequencing, and antibody synthesis localised these mutations to B cells, confirmed some to be self-reactive, and identified clones carrying multiple hits. We found widespread TNFRSF14 biallelic loss, and clones with as many as 4-6 driver mutations. Whilst each clone accounts for a small fraction of cells (typically <1%), the myriad mutant clones in each donor amounted to a substantial fraction of B cells harbouring driver mutations. Our results support the hypothesis that somatic mutations in autoimmune lymphocytes may allow them to escape tolerance constraints through a polyclonal cascade of somatic evolution, providing new insights into the molecular basis of autoimmune disease.",
            "content": "Our immune system contains multiple checkpoints to prevent the activation of self-reactive lymphocytes. How some lymphocytes escape these constraints to cause autoimmune disease remains poorly understood. A long-standing hypothesis posits that somati... [1474 chars]",
            "url": "https://www.nature.com/articles/s41586-026-10493-9?error=cookies_not_supported&code=90577582-5b22-4279-b780-db3603a77da1",
            "image": "https://www.nature.com/static/images/favicons/nature/favicon-48x48-b52890008c.png",
            "publishedAt": "2026-04-14T21:53:05Z",
            "lang": "en",
            "source": {
                "id": "7abf0df285fbe93cdccffcc7c4088737",
                "name": "Nature",
                "url": "https://www.nature.com"
            }
        },
        {
            "id": "9a7154afd1b68a86ce9cd6f74957f4de",
            "title": "People Debunk 45 Health Myths They Wish You’d Stop Believing",
            "description": "We all know that one person who subscribes to the most ridiculous health myths. They’re the ones who believe that urine is sterile, salt is bad for you, and vaccines cause autism. And they would choose to stick to their guns, despite the numerous debunkings. Here are more of those old wives' tales mentioned in a recent Reddit thread. You may find the usuals: fear of fat and gluten, and walking outside after showering gets you sick. You may also come across more ludicrous claims, like how organic",
            "content": "We all know that one person who subscribes to the most ridiculous health myths. They’re the ones who believe that urine is sterile, salt is bad for you, and vaccines cause autism. And they would choose to stick to their guns, despite the numerous deb... [8992 chars]",
            "url": "https://www.aol.com/articles/people-debunk-45-health-myths-030102401.html",
            "image": "https://s.yimg.com/os/en/aol_bored_panda_979/2ad3506d9b931195f02ad439f6ccf2b2",
            "publishedAt": "2026-04-14T16:03:54Z",
            "lang": "en",
            "source": {
                "id": "4ff2d0fa568705d6b87ce5c9e310a16d",
                "name": "AOL.com",
                "url": "https://www.aol.com"
            }
        }
    ]
}