United States Health News API

{
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            "id": "d7daeec377c3624be1d13e233f9287cc",
            "title": "Cardiologists Share 6 Surprising Lifestyle Habits That Boost Heart Health",
            "description": "Cardiologists share the important advice they give patients that you can also incorporate into your daily routine.",
            "content": "Heart disease is the leading cause of death in America, making it a health concern worth paying attention to. But while heart disease is scary, research suggests that the majority of cardiovascular issues are preventable. That means you may be able t... [6105 chars]",
            "url": "https://www.aol.com/articles/cardiologists-share-6-surprising-lifestyle-140000687.html",
            "image": "https://s.yimg.com/cv/apiv2/aolfp/images/og-image.png",
            "publishedAt": "2026-02-19T00:36:37Z",
            "lang": "en",
            "source": {
                "id": "4ff2d0fa568705d6b87ce5c9e310a16d",
                "name": "AOL.com",
                "url": "https://www.aol.com"
            }
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        {
            "id": "ae80996fa63f05d16b5acf3b575c59b4",
            "title": "The big fat jab divide: why middle-class women are buying them",
            "description": "New research has shown that is the key demographic driving weight-loss prescriptions, particularly aged 30-50. I spend £200 a month and have lost 10kg, says Olivia Falcon",
            "content": "I guess you could say I was an early adopter of GLP-1 medication. I started taking Ozempic in April 2023 after a year of health problems. I certainly wasn’t obese, and to most people I didn’t look overweight, but the scales and blood tests told a dif... [12722 chars]",
            "url": "https://www.thetimes.com/life-style/health-fitness/article/ozempic-mounjaro-weight-jab-class-ksr9lknjj",
            "image": "https://www.thetimes.com/imageserver/image/%2F247bfe98-e65f-4308-b33b-12f96a6dbe4a.jpg?crop=1600%2C900%2C0%2C0&resize=1200",
            "publishedAt": "2026-02-18T23:00:00Z",
            "lang": "en",
            "source": {
                "id": "9e0e1039092ec85a0b069e08b66bb337",
                "name": "The Times",
                "url": "https://www.thetimes.com"
            }
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        {
            "id": "e9884e9b0557ca1491fff8afd670f40d",
            "title": "Single-cell and isoform-specific translational profiling of the mouse brain",
            "description": "The brain displays the richest repertoire of post-transcriptional mechanisms regulating mRNA translation1–11. Among these, alternative splicing has been shown to drive cell-type specificity and, when disrupted, is strongly linked to neurological disorders12–17. However, genome-wide measurements of mRNA translation with isoform sensitivity at single-cell resolution have not been achieved. To address this, we deployed Surveying Ribosomal Targets by APOBEC-Mediated Profiling (Ribo-STAMP) coupled with short-read and long-read single-cell RNA sequencing in the brain18. We generated the first isoform-sensitive single-cell translatomes of the mouse hippocampus at postnatal day 25, discovering cell-type-specific translation of 3,857 alternative transcripts across 1,641 genes and identifying isoforms of the same genes undergoing differential translation within and across 8 different cell types. We defined high and low translational states in CA1 and CA3 neurons, with synaptic and metabolic genes enriched in high states. We found that CA3 exhibited higher basal translation compared with CA1, as confirmed by metabolic labelling of newly synthesized proteins and immunohistochemistry of translational machinery components. This accessible platform will expand our understanding of how cell-type-specific and isoform-specific translation drives brain physiology and disease. Post-transcriptional regulation of mRNA translation was explored using Ribo-STAMP and single-cell RNA sequencing to reveal cell-type-specific and isoform-specific translation patterns across hippocampal neuronal and non-neuronal cell types, highlighting functional differences between CA1 and CA3.",
            "content": "Molecular cloning and AAV production\nThe original Ribo-STAMP construct consisted of a Tet-On hRPS2–APOBEC lentiviral expression vector, with a human phosphoglycerate kinase (PGK) promoter driving the expression of rtTA and pac, designed for generatio... [46489 chars]",
            "url": "https://www.nature.com/articles/s41586-026-10118-1?error=cookies_not_supported&code=76f389b5-793f-4a87-a396-e70f0abb0ec5",
            "image": "https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs41586-026-10118-1/MediaObjects/41586_2026_10118_Fig1_HTML.png",
            "publishedAt": "2026-02-18T22:48:22Z",
            "lang": "en",
            "source": {
                "id": "7abf0df285fbe93cdccffcc7c4088737",
                "name": "Nature",
                "url": "https://www.nature.com"
            }
        }
    ]
}