Singapore Science News API

{
    "totalArticles": 15520,
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        {
            "id": "e9c8430115b94691fc4cc7f37df6bdf6",
            "title": "NASA's crewed Artemis II launch gets pushed back again, this time due to a helium issue",
            "description": "NASA says it's rolling the SLS rocket off the launch pad so it can get to the bottom of a helium flow issue it ran into over the weekend.",
            "content": "It looks like a March launch is no longer in the cards for Artemis II, NASA's first crewed trip to the moon's vicinity since the final Apollo mission over 50 years ago. While preparations were underway at the Kennedy Space Center for a launch as soon... [1946 chars]",
            "url": "https://www.engadget.com/science/space/nasas-crewed-artemis-ii-launch-gets-pushed-back-again-this-time-due-to-a-helium-issue-231010042.html",
            "image": "https://s.yimg.com/ny/api/res/1.2/aB8QFeAH5wvv.AWPBhY6VQ--/YXBwaWQ9aGlnaGxhbmRlcjt3PTEyMDA7aD02NzU-/https://d29szjachogqwa.cloudfront.net/images/user-uploaded/ksc-20260210-ph-jbs01-0126~large.jpg",
            "publishedAt": "2026-02-22T23:10:10Z",
            "lang": "en",
            "source": {
                "id": "48e27292ccc1733d7eefd6a41c5655d4",
                "name": "Engadget",
                "url": "https://www.engadget.com"
            }
        },
        {
            "id": "644918416a758417f27ce591b14250eb",
            "title": "Pseudolysogeny-mediated evolutionary trade-offs favor phage therapy by limiting antibiotic resistance and virulence in Cutibacterium acnes",
            "description": "Phage therapy has mostly focused on strictly lytic phages, yet the ecological and evolutionary implications of pseudolysogeny remain poorly understood. Pseudolysogeny—where a phage genome persists in a non-integrated, latent state within the host—has been largely overlooked due to concerns about therapeutic efficacy. Here, we demonstrate that pseudolysogeny in Cutibacterium acnes confers superinfection resistance but imposes substantial fitness costs, including reduced biofilm formation, impaired interspecies competitiveness, and reversal of antibiotic resistance. Pseudolysogenic phages were also capable of killing starved C. acnes cells through direct lytic replication. No evidence of transduction of clindamycin resistance by these phages was detected. In a 3-month proof-of-concept study, topical application of a pseudolysogenic phage significantly reduced C. acnes abundance, acne lesions, and inflammation, with no adverse effects and persistence of viable phages post-treatment. Importantly, no phage-resistant C. acnes clones were detected during the in vivo study, likely due to the evolutionary trade-offs associated with pseudolysogeny that diminish the bacterial ecological fitness. These findings highlight pseudolysogeny as a mechanism that can be leveraged to enhance phage therapy outcomes while maintaining microbiome stability and limiting antibiotic resistance evolution.",
            "content": "Jappe, U. Pathological Mechanisms of Acne with Special Emphasis on Propionibacterium acnes and Related Therapy. Acta Derm. Venereol. 83, 241 (2003).\nMorshed, S. M. Understanding the impact of acne vulgaris and associated psychological distress on sel... [7500 chars]",
            "url": "https://www.nature.com/articles/s41598-026-40701-5?error=cookies_not_supported&code=1812f717-008d-4e57-8355-df4335c5b05f",
            "image": "https://www.nature.com/static/images/favicons/nature/favicon-48x48-b52890008c.png",
            "publishedAt": "2026-02-22T10:51:54Z",
            "lang": "en",
            "source": {
                "id": "7abf0df285fbe93cdccffcc7c4088737",
                "name": "Nature",
                "url": "https://www.nature.com"
            }
        },
        {
            "id": "e94c7b5e8b6a616d5a8c8172919dcc04",
            "title": "AI Spots New Electron Crystal Within Graphene Layers",
            "description": "Researchers have discovered a novel, self-assembled state of electrons in moiré patterns where pairs form molecules that arrange into a crystalline structure, depleting a quarter of the available space and demonstrating unexpected collective behaviour.",
            "content": "Scientists have uncovered a novel ground state of matter within artificial graphene, revealing a paired Wigner crystal formed through an unexpected self-assembly process. Conor Smith from the Center for Computational Quantum Physics at the Flatiron I... [10499 chars]",
            "url": "https://quantumzeitgeist.com/ai-spots-electron-crystal-within-graphene-layers/",
            "image": "https://quantumzeitgeist.com/wp-content/uploads/Image_fx-3-54.jpg",
            "publishedAt": "2026-02-21T00:59:41Z",
            "lang": "en",
            "source": {
                "id": "57e0972312d283bae70e31e5b557783c",
                "name": "Quantum Zeitgeist",
                "url": "https://quantumzeitgeist.com"
            }
        }
    ]
}