Singapore Health News API

{
    "totalArticles": 49828,
    "articles": [
        {
            "id": "59cb96485e450b389c4203640cf759fb",
            "title": "Flu vaccines didn't work that well in the U.S., officials find",
            "description": "As the U.S. flu season winds down, health officials say the flu vaccine didn't work very well, with one of its worst effectiveness rates in more than a decade. A new strain that dominated the early winter was not well matched to the vaccine, leading to an intense early onslaught…",
            "content": "As the U.S. flu season winds down, health officials say the flu vaccine didn't work very well, with one of its worst effectiveness rates in more than a decade.\nA new strain that dominated the early winter was not well matched to the vaccine, leading ... [3551 chars]",
            "url": "https://japantoday.com/category/features/health/flu-vaccines-didn't-work-that-well-in-the-us-officials-find",
            "image": "https://media.japantoday.com/img/store/60/f9/4f18302c5356e4b07c02729b1bbc0d3020d4/download/_w1700.jpeg",
            "publishedAt": "2026-03-14T21:23:13Z",
            "lang": "en",
            "source": {
                "id": "b6e16e937954be66de0f0475c3640971",
                "name": "Japan Today",
                "url": "https://japantoday.com"
            }
        },
        {
            "id": "97f280a1043cf4cc46756f17102d8d6d",
            "title": "Multidrug resistant Acinetobacter baumannii shows epidemiology and transmission patterns in a China tertiary hospital ICU",
            "description": "This study aimed to investigate the distribution characteristics, resistance mechanisms, and transmission dynamics of multidrug-resistant Acinetobacter baumannii (MDRAB) in the ICU of a hospital in China. A total of 272 clinical MDRAB isolates were collected from the ICU of a single hospital between 2013 and 2025. Resistance genes associated with β-lactams, carbapenems, and aminoglycosides were detected, and antimicrobial susceptibility testing was performed to assess resistance phenotypes. Molecular typing, including sequence typing (ST) and pulsed-field gel electrophoresis (PFGE), was conducted on selected patient and environmental isolates to further analyze in-hospital transmission patterns. Of the 272 isolates, approximately 53% were derived from respiratory specimens. All isolates exhibited 100% resistance to carbapenems, which was consistent with the universal presence of the blaOXA−23 gene. Environmental surveillance revealed a high isolation rate of A. baumannii in areas surrounding infected patients, particularly those with respiratory infections. PFGE analysis showed that some environmental isolates exhibited different patterns from the corresponding clinical strains, suggesting potential microevolution and involvement in the ongoing in-hospital dissemination of MDRAB. This study systematically analyzed the resistance characteristics and transmission patterns of 272 MDRAB isolates collected from a hospital ICU in China between 2013 and 2025. The results of the study showed that blaOXA−23 may play an important role in carbapenem resistance. Both clinical and environmental isolates exhibited multidrug resistance and the ability to persist in hospital environments. PFGE analysis indicated possible microevolution among environmental strains, potentially facilitating the sustained transmission of MDRAB within the hospital setting.",
            "content": "Adeyemi, F. M. et al. Carbapenem-resistance in Acinetobacter baumannii: Prevalence, antibiotic resistance profile and carbapenemase genes in clinical and hospital environmental strains. BMC Infect. Dis. 25, 786. https://doi.org/10.1186/s12879-025-111... [8671 chars]",
            "url": "https://www.nature.com/articles/s41598-026-43777-1?error=cookies_not_supported&code=ed2080fd-ded0-40a3-b03e-134afa4b14f5",
            "image": "https://www.nature.com/static/images/favicons/nature/favicon-48x48-b52890008c.png",
            "publishedAt": "2026-03-14T16:09:28Z",
            "lang": "en",
            "source": {
                "id": "7abf0df285fbe93cdccffcc7c4088737",
                "name": "Nature",
                "url": "https://www.nature.com"
            }
        },
        {
            "id": "24184b1b7e823ee4baac98a1f60efb38",
            "title": "GLP-1RAs Could Help Type 2 Diabetes and Brain Cancer",
            "description": "GLP-1RAs could substantially reduce mortality in patients with brain metastases and Type 2 diabetes. Read more.",
            "content": "PATIENTS with brain metastases and Type 2 diabetes using glucagon-like peptide-1 receptor agonists (GLP-1RA) have a near 40% lower risk of death over 3 years compared with nonusers, a 2026 retrospective cohort study has found.\nComorbid Type 2 Diabete... [2243 chars]",
            "url": "https://www.emjreviews.com/diabetes/news/glp-1ras-can-benefit-patients-with-brain-cancer-and-type-2-diabetes/",
            "image": "https://www.emjreviews.com/wp-content/uploads/2026/03/4pm-diab-2.jpg",
            "publishedAt": "2026-03-14T16:05:28Z",
            "lang": "en",
            "source": {
                "id": "a9f12901925fcfb02f9d57b5db396471",
                "name": "European Medical Journal",
                "url": "https://www.emjreviews.com"
            }
        }
    ]
}