Singapore Health News API

{
    "totalArticles": 51522,
    "articles": [
        {
            "id": "1b10285a82503ab86e1fca50b6b4c439",
            "title": "AI tool helps paralysed patients communicate through blinks and focus; hospital to trial device",
            "description": "Some 30 patients at Tan Tock Seng Hospital will be involved in the trial starting in June. Read more at straitstimes.com.",
            "content": "SINGAPORE - Patients with severe movement and speech impairment will soon be able to communicate more quickly with their caregivers through the use of an artificial intelligence neural-detection device created by a local start-up.\nTan Tock Seng Hospi... [6028 chars]",
            "url": "https://www.straitstimes.com/tech/ai-tool-helps-paralysed-patients-communicate-through-blinks-and-focus-hospital-to-trial-device",
            "image": "https://cassette.sphdigital.com.sg/image/straitstimes/ca29da3686a2827ea1527e9e923629783890af45cbbb16a004fbcd52b6a624f0",
            "publishedAt": "2026-04-18T21:00:00Z",
            "lang": "en",
            "source": {
                "id": "739b615c65becd670ee152cab7f8c439",
                "name": "The Straits Times",
                "url": "https://www.straitstimes.com"
            }
        },
        {
            "id": "9d49d75d6796719c9117ec650aac8476",
            "title": "Wastewater intelligence predicts the emergence of clinically-relevant and drug-resistant Candidozyma auris at healthcare facilities",
            "description": "The rapid evolution of antifungal resistance in Candidozyma auris (formerly Candida auris) presents significant challenges for conventional public health surveillance methods, particularly in detecting emergent and highly transmissible drug-resistant variants. Here, using wastewater-based epidemiology tools initially developed during the COVID-19 pandemic, we implement a high-resolution, facility-level early warning system to monitor C. auris infections and resistance patterns. Our evaluation across Southern Nevada demonstrates that upstream sewage monitoring at healthcare facilities provides significant sensitivity (p < 0.001) compared to wastewater treatment plant sampling. By combining amplicon sequencing and MALDI-TOF mass spectrometry, we identify clinically-relevant, resistance-associated variants in wastewater samples, while whole-genome sequencing reveals >90% genomic concordance between 443 wastewater-derived genomes and 2945 clinical isolates. We also detect previously unreported subclades and resistance mutations, including FKS1 Phe635Leu and co-occurring ERG11/FKS1 variants in wastewater samples up to nearly five months before their appearance in clinical settings. Transcriptomic profiling of drug-resistant isolates under antifungal and stress conditions identifies previously uncharacterized adaptation mechanisms, including differential regulation of ribosomal assembly pathways and cell cycle checkpoints. These findings highlight how wastewater intelligence can enhance traditional public health approaches for early detection and monitoring of C. auris outbreaks and antifungal resistance. Facility-level wastewater monitoring detected emerging Candidozyma auris subclades and resistance mutations 13–143 days before clinical identification, supported by >90% genomic concordance between wastewater-derived and clinical isolate genomes.",
            "content": "Satoh, K. et al. Candida auris sp. nov., a novel ascomycetous yeast isolated from the external ear canal of an inpatient in a Japanese hospital. Microbiol. Immunol. 53, 41–44 (2009).\nO’Meara, T. R. Understanding pathogen emergence through the lens of... [10820 chars]",
            "url": "https://www.nature.com/articles/s41467-026-71960-5?error=cookies_not_supported&code=ddfdba70-568d-480c-b4ce-f657b1e70dfe",
            "image": "https://www.nature.com/static/images/favicons/nature/favicon-48x48-b52890008c.png",
            "publishedAt": "2026-04-18T20:37:30Z",
            "lang": "en",
            "source": {
                "id": "7abf0df285fbe93cdccffcc7c4088737",
                "name": "Nature",
                "url": "https://www.nature.com"
            }
        },
        {
            "id": "fb8aadce0a9dcb3e3db514d720798cd7",
            "title": "Humans evolved faster than expected after farming reshaped life",
            "description": "A new study finds natural selection has reshaped hundreds of human genes in the past 10,000 years, driven by farming, disease, and lifestyle.",
            "content": "Natural selection has reshaped hundreds of human genes in the past 10,000 years, far more than scientists had previously recognized.\nThe study reframes recent human evolution as an active process driven by changing diets, diseases, and ways of living... [5614 chars]",
            "url": "https://www.earth.com/news/humans-evolved-faster-than-expected-after-farming-reshaped-life/",
            "image": "https://cff2.earth.com/uploads/2026/04/18110520/human-evolution-farming-.jpg",
            "publishedAt": "2026-04-18T20:15:00Z",
            "lang": "en",
            "source": {
                "id": "fca72a05020e12df547eedb79c870663",
                "name": "Earth.com",
                "url": "https://www.earth.com"
            }
        }
    ]
}