Singapore Health News API

{
    "totalArticles": 50120,
    "articles": [
        {
            "id": "4f30982708831caa0ef98f132448d646",
            "title": "A novel approach to improving survival in treatment-resistant cancers",
            "description": "Researchers at the National University of Singapore (NUS) have identified a protein called tyrosine phosphatase 1B (PTP1B) as a potential \"switch\" that can modulate a type of cancer cell death known as immunogenic cell death (ICD).",
            "content": "Researchers at the National University of Singapore (NUS) have identified a protein called tyrosine phosphatase 1B (PTP1B) as a potential \"switch\" that can modulate a type of cancer cell death known as immunogenic cell death (ICD).\nICD is a special t... [2426 chars]",
            "url": "https://www.news-medical.net/news/20260306/A-novel-approach-to-improving-survival-in-treatment-resistant-Cancers.aspx",
            "image": "https://www.news-medical.net/image-handler/picture/2014/7/174318220-620x480.jpg",
            "publishedAt": "2026-03-06T05:05:00Z",
            "lang": "en",
            "source": {
                "id": "f2ca7a45d20357cb42858868cb4a4946",
                "name": "News-Medical",
                "url": "https://www.news-medical.net"
            }
        },
        {
            "id": "488f457bd816fc9da25b3ffd415fffaf",
            "title": "Acute Necrotizing Encephalopathy Related to Non",
            "description": "Acute necrotizing encephalopathy (ANE) is a rare, rapidly progressive, and severe immune-mediated neurological disorder that frequently leads to severe neurological sequelae or mortality. Viral infection represents a common pathogenic factor, while cytokine storm constitutes the primary pathogenic mechanism. ANE is a distinct clinical entity characterized by specific clinical and imaging features. Immunomodulatory therapy and anti-cytokine interventions represent effective treatment strategies for ANE.",
            "content": "1. Introduction\nAcute necrotizing encephalopathy (ANE) is a rare and severe form of acute encephalopathy, mainly marked by seizures or altered consciousness. ANE often follows a viral infection, most commonly influenza, and typically involves multipl... [9968 chars]",
            "url": "https://www.scirp.org/journal/paperinformation?paperid=149973",
            "image": "https://file.scirp.org/image/jbm2024061816374557.jpg",
            "publishedAt": "2026-03-06T03:51:32Z",
            "lang": "en",
            "source": {
                "id": "48f641eab3fd1aa330e8db4cb1cfe74e",
                "name": "SCIRP Open Access",
                "url": "https://www.scirp.org"
            }
        },
        {
            "id": "7ea87c7b97499a994565916d65048c93",
            "title": "A Case of a Juvenile Endometrial Polyp Presenting with Intractable Menorrhagia in an Adolescent Girl",
            "description": "Background: Endometrial polyps are exceptionally rare in adolescents, in whom heavy menstrual bleeding (HMB) is usually due to anovulatory cycles or coagulation disorders. Optimal postoperative management in this age group, particularly regarding recurrence prevention, remains unclear. Case: A 14-year-old girl presented with persistent HMB unresponsive to combined estrogen–progestin therapy. Laboratory tests showed no coagulation or endocrine abnormalities. Imaging revealed an endometrial mass extending into the cervical canal, and hysteroscopic resection confirmed a benign endometrial polyp. Given her anovulatory background and presumed unopposed estrogen exposure, postoperative treatment with a low-dose combined oral contraceptive (COC) was initiated. Over a 3-year follow-up, regular cycles were maintained without recurrence. Conclusion: Structural causes of HMB, such as endometrial polyps or other organic uterine lesions, should be considered when adolescents remain symptomatic despite hormonal therapy. COCs may serve as an effective postoperative strategy to prevent the recurrence of estrogen-dependent lesions such as endometrial polyps in patients with persistent anovulatory cycles.",
            "content": "1. Introduction\nHeavy menstrual bleeding (HMB) in adolescents is most commonly caused by anovulatory cycles associated with hypothalamic–pituitary–ovarian axis immaturity, followed by coagulation disorders, particularly von Willebrand disease. In con... [12424 chars]",
            "url": "https://www.scirp.org/journal/paperinformation?paperid=149971",
            "image": "https://file.scirp.org/image/ojog2024060616140818.png",
            "publishedAt": "2026-03-06T03:51:31Z",
            "lang": "en",
            "source": {
                "id": "48f641eab3fd1aa330e8db4cb1cfe74e",
                "name": "SCIRP Open Access",
                "url": "https://www.scirp.org"
            }
        }
    ]
}