Ireland Health News API

{
    "totalArticles": 2722418,
    "articles": [
        {
            "id": "cb1d93eace1f345c5cea60b835393c5c",
            "title": "Switching Off One Crucial Protein Appears to Reverse Brain Aging in Mice",
            "description": "A protein called ferritin light chain 1 (FTL1) may play a significant role in brain aging, a new study reveals, giving scientists a new target for understanding and potentially preventing brain deterioration and disease.",
            "content": "A protein called ferritin light chain 1 (FTL1) may play a significant role in brain aging, a new study reveals, giving scientists a new target for understanding and potentially preventing brain deterioration and disease.\nFTL1 was brought to light thr... [3135 chars]",
            "url": "https://www.sciencealert.com/switching-off-one-crucial-protein-appears-to-reverse-brain-aging-in-mice",
            "image": "https://www.sciencealert.com/images/2025/08/BrokenBrain.jpg",
            "publishedAt": "2025-09-03T00:36:51Z",
            "lang": "en",
            "source": {
                "id": "76a2943c768c5c3be7d790e609b40403",
                "name": "ScienceAlert",
                "url": "https://www.sciencealert.com",
                "country": "ie"
            }
        },
        {
            "id": "78182ac7095c903b55682d8ff7ce311c",
            "title": "Acute versus acute-on-chronic liver failure: comparative analysis of clinical outcomes in Beijing, China",
            "description": "Acute liver failure (ALF) and acute-on-chronic liver failure (ACLF) pose significant threats to patient outcomes, frequently resulting in multiple organ dysfunction syndrome (MODS) and elevated mortality rates. This study investigates MODS outcomes among ALF and ACLF patients in China, identifying key factors that influence mortality and prognosis. A retrospective cohort analysis was conducted at a specialized tertiary hospital in Beijing, covering the period from June 2009 to May 2022, which included 585 patients:195 with ALF and 390 with ACLF. Among these, 61% of ALF patients and 45.1% of ACLF patients developed MODS. ALF patients exhibited a higher incidence of organ failures and significantly higher median admission critical illness scores. Multivariate logistic regression analysis identified age, number of organ failures, and platelet count as independent predictors of 90-day mortality. Kaplan-Meier survival hazards analysis revealed significantly higher 90-day cumulative mortality rates for ALF patients compared to ACLF patients (33.8% vs. 25.9%, p = 0.009). Approximately 50% of liver failure patients progress to MODS, with ALF patients demonstrating a higher incidence of MODS and poorer 90-day prognoses.",
            "content": "In this study, drug-induced (34.4%) and HBV infection (26.2%) emerged as the predominant factors in patients with ALF, while HBV infection (63.6%) and alcohol-associated factors (16.4%) were identified as key contributors in patients with ACLF. These... [10420 chars]",
            "url": "https://bmcgastroenterol.biomedcentral.com/articles/10.1186/s12876-025-04234-x",
            "image": "https://static-content.springer.com/image/art%3A10.1186%2Fs12876-025-04234-x/MediaObjects/12876_2025_4234_Fig1_HTML.png",
            "publishedAt": "2025-09-03T00:18:10Z",
            "lang": "en",
            "source": {
                "id": "beb2376c1ae2a072b3c097862fc7b5d8",
                "name": "BMC Gastroenterology",
                "url": "https://bmcgastroenterol.biomedcentral.com",
                "country": "ie"
            }
        },
        {
            "id": "3d29ecbf4af61e62a390f75e57a773a8",
            "title": "Urgent action needed to make UK cancer care fair, charity warns",
            "description": "Macmillan Cancer Support said too many patients feel they need to be ‘in the right place, at the right time’.",
            "content": "More than a third of patients said they had to travel for an hour or more for a test or scan, or for treatment\nAn estimated four in 10 people with cancer in the UK have struggled to access care because of where they live, according to analysis.\nSome ... [4140 chars]",
            "url": "https://www.irishnews.com/news/uk/urgent-action-needed-to-make-uk-cancer-care-fair-charity-warns-X4ETP7RZR5PBXGZU45IINF2ULA/",
            "image": "https://www.irishnews.com/resizer/v2/56EJBW2PQ5O7FK5YTQMKUZCDLI.jpg?smart=true&auth=72160dc0057cdb537a65530aab1aed22d426140826393b3fb62a6b93a5ee310c&width=1200&height=630",
            "publishedAt": "2025-09-02T23:01:00Z",
            "lang": "en",
            "source": {
                "id": "f16efc96d0de1a6b5398d732cce1fe7a",
                "name": "The Irish News",
                "url": "https://www.irishnews.com",
                "country": "ie"
            }
        }
    ]
}