Canada Health News API

{
    "totalArticles": 300446,
    "articles": [
        {
            "id": "992b148de4d4f556a2a2bcdcd5c76bcd",
            "title": "Prenatal diisononyl phthalate exposure induces the development of pulmonary dysplasia in offspring",
            "description": "As a widely used plasticizer, diisononyl phthalate (DINP) has been considered an emerging environmental pollutant. Epidemiological evidence shows that prenatal DINP exposure is linked to an increased risk of lung diseases in offspring and adults. However, little is known about their relationship at the molecular level. We exposed pregnant mice to DINP (100 mg/kg/day) by intragastric administration throughout gestation. On postnatal days (PNDs) 21 and 42, offspring were sacrificed and the lungs were collected. We found that prenatal DINP exposure significantly caused hypoalveolarization in male offspring on PND 21, which was reversed during postnatal development. Moreover, prenatal DINP exposure significantly caused pulmonary fibrosis in male offspring on PND 42. However, neither of these changes was observed in female offspring. KEGG enrichment showed that differentially expressed genes (DEGs) in the lungs of male offspring were closely associated with the calcium signaling and IL-17 signaling pathways. Importantly, decreased Htr4 expression might contribute to hypoalveolarization, and the elevated Il-17a expression might be responsible for prenatal DINP exposure-induced pulmonary fibrosis in male offspring. Our results demonstrated that prenatal DINP exposure had a persistent impact on lung development in male offspring, including early-stage impaired alveolarization and later-stage fibrosis.",
            "content": "Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original... [625 chars]",
            "url": "https://www.nature.com/articles/s41598-026-50939-8?error=cookies_not_supported&code=9bb9e03c-7b39-4428-a0b0-83670c9b4de0",
            "image": "https://www.nature.com/static/images/favicons/nature/favicon-48x48-b52890008c.png",
            "publishedAt": "2026-05-03T16:52:30Z",
            "lang": "en",
            "source": {
                "id": "7abf0df285fbe93cdccffcc7c4088737",
                "name": "Nature",
                "url": "https://www.nature.com"
            }
        },
        {
            "id": "2e096602f58c838319664395129ab264",
            "title": "Scientists just discovered what coffee is really doing to your gut and brain",
            "description": "Coffee doesn’t just energize—it actively reshapes the gut and mind. Researchers found that both caffeinated and decaf coffee altered gut bacteria in ways linked to better mood and lower stress. Decaf even improved learning and memory, while caffeine boosted focus and reduced anxiety. Together, they show coffee works through multiple pathways beyond just caffeine.",
            "content": "The findings, published in Nature Communications and supported by the Institute for Scientific Information on Coffee (ISIC), show that regularly drinking both caffeinated and decaffeinated coffee can shape the gut microbiome and influence mood and st... [3949 chars]",
            "url": "https://www.sciencedaily.com/releases/2026/05/260502233911.htm",
            "image": "https://www.sciencedaily.com/images/1920/woman-enjoying-morning-coffee-and-sunshine.webp",
            "publishedAt": "2026-05-03T16:21:24Z",
            "lang": "en",
            "source": {
                "id": "81a05fd2712964dbdb32b1c6a27646fd",
                "name": "ScienceDaily",
                "url": "https://www.sciencedaily.com"
            }
        },
        {
            "id": "051ebaa48fece1f2f3a3d05866d43c77",
            "title": "Brossard au cœur d'une enquête nationale sur la santé",
            "description": "Brossard a été retenue parmi 16 villes canadiennes pour participer à l'Enquête canadienne sur les mesures de la santé (ECMS), une vaste opération de Statistique Canada. Environ 850 ménages de la ville seront sélectionnés aléatoirement pour prendre part à cette démarche scientifique.",
            "content": "Brossard a été retenue parmi 16 villes canadiennes pour participer à l’Enquête canadienne sur les mesures de la santé (ECMS), une vaste opération de Statistique Canada. Environ 850 ménages de la ville seront sélectionnés aléatoirement pour prendre pa... [1196 chars]",
            "url": "http://lecourrierdusud.ca/brossard-au-coeur-dune-enquete-nationale-sur-la-sante/",
            "image": "http://lecourrierdusud.ca/wp-content/uploads/sites/9/2025/10/1759772822_courses.jpg",
            "publishedAt": "2026-05-03T16:01:00Z",
            "lang": "fr",
            "source": {
                "id": "ab7fb43b510f72d1bb299ae6e808e5c7",
                "name": "Le Courrier du sud",
                "url": "http://lecourrierdusud.ca"
            }
        }
    ]
}