Uganda Health News API

{
    "totalArticles": 7062,
    "articles": [
        {
            "id": "638a78aaaeeb36c0093644149e5368ce",
            "title": "Warning to women amid shortages of some HRT products",
            "description": "Two brands of HRT patches, including Estradot transdermal and FemSeven Conti patches, have been affected, the Department of Health has said.",
            "content": "Pharmacist Paul Irvine said he understood that women \"are concerned\" but urged them to speak to their GP or local chemist who could advise them about alternatives.\nThe warning follows official confirmation from the Department of Health that supplies ... [2658 chars]",
            "url": "https://www.bbc.com/news/articles/cwr7yz5x7pj0o",
            "image": "https://ichef.bbci.co.uk/news/1024/branded_news/3f08/live/af862a80-c7f0-11f1-bc2e-018d645d8d21.jpg",
            "publishedAt": "2026-10-14T23:01:00Z",
            "lang": "en",
            "source": {
                "id": "f331a5ed3965fb59761dfcecfc7e7a34",
                "name": "BBC",
                "url": "https://www.bbc.com"
            }
        },
        {
            "id": "6051ae2d82261900ca4b4634a94bc485",
            "title": "Modelling mouse embryogenesis from chemically induced totipotent stem cells",
            "description": "The ability to faithfully initiate embryogenesis from a single, induced non-germline cell type, akin to the totipotent blastomeres, remains a considerable challenge in developmental and synthetic biology1–14. Here we established conditions that enable the continuous ex utero development of mouse embryo models (EMs), starting solely from the chemically induced totipotent-like stem cells (ciTotiSCs)15 and spanning the pre-implantation morula, blastocysts and post-gastrulation stages with both embryonic and extraembryonic compartments. These ciTotiSCs self-organized into blastocyst-like structures that closely resembled natural blastocysts in both morphology and lineage segregation. The resulting ciTotiSC-derived EMs (ciToti-EMs) successfully progressed through key developmental milestones, including gastrulation, embryonic axis formation, haematopoiesis and early organogenesis, closely resembling embryonic day 8.5 (E8.5) natural embryos (NEs). Furthermore, extended culture led to the development of functional cardiac tissues in ciToti-EMs, highly comparable to those of E10.5 NEs. These findings demonstrate an extraordinary ability of a single induced cell type, ciTotiSCs, to autonomously recapitulate the complete spectrum of early mouse embryogenesis. Our ciToti-EM system provides a powerful model for investigating mammalian embryonic development and opens new avenues for creating multicellular organisms from non-germline cells. A mouse embryo model derived from chemically induced totipotent-like stem cells progresses through key developmental milestones, including gastrulation, embryonic axis formation, haematopoiesis and early organogenesis.",
            "content": "a, Representative images of mESCs carrying MERVL-tdTomato and OCT4-GFP reporters cultured in 2i/L, TAW, or TAWa medium. Lower panel, heat maps showing their relative expression of classical totipotency- and pluripotency-associated genes. Scale bars, ... [22722 chars]",
            "url": "https://www.nature.com/articles/s41586-026-11164-5?error=cookies_not_supported&code=0b7a7912-b360-4260-af4c-0e2861bd86e7",
            "image": "https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs41586-026-11164-5/MediaObjects/41586_2026_11164_Fig1_HTML.png",
            "publishedAt": "2026-10-14T22:52:30Z",
            "lang": "en",
            "source": {
                "id": "7abf0df285fbe93cdccffcc7c4088737",
                "name": "Nature",
                "url": "https://www.nature.com"
            }
        },
        {
            "id": "7b866dac1d867cc246ae9c5fa81a5019",
            "title": "Simple, noninvasive technique can assess collagen in the skin of scleroderma patients",
            "description": "Scleroderma (systemic sclerosis) is a rare, chronic autoimmune disease that causes the body to produce too much collagen, leading to the hardening and thickening of the skin and internal organs. For more than 50 years, physicians have relied on manually pinching the skin to assess its thickness, a subjective approach that remains central to the diagnosis of systemic sclerosis, assessment of disease extent and progression and monitoring of response to treatment.",
            "content": "Scleroderma (systemic sclerosis) is a rare, chronic autoimmune disease that causes the body to produce too much collagen, leading to the hardening and thickening of the skin and internal organs. For more than 50 years, physicians have relied on manua... [3396 chars]",
            "url": "https://medicalxpress.com/news/2026-10-simple-noninvasive-technique-collagen-skin.html",
            "image": "https://scx2.b-cdn.net/gfx/news/hires/2026/inflammed-skin.jpg",
            "publishedAt": "2026-10-14T22:30:34Z",
            "lang": "en",
            "source": {
                "id": "fc12437cc984742bf9a97820262ab48a",
                "name": "Medical Xpress",
                "url": "https://medicalxpress.com"
            }
        }
    ]
}